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  • Physicians who treat opioid addiction also provide the option of utilizing 'medication-assisted treatment', and the most common medications utilized in the treatment of opioid dependence today are methadone, naltrexone, and buprenorphine (Suboxone).

    Using two separate drugs to lose weight can be very effective there are combinations before the FDA now awaiting approval. When dealing with weight-loss and the people that go through it you should err to the side of caution and let the FDA do its job and demand some study be done in order that the public understands the side effects and perils associated with the medications before we take them. Keep in mind that drug companies have been in business to make money and that they would say anything to keep people on his or her medications.

    Researchers found that participants using this drug for any year, dropped excess weight within four weeks and have kept the extra weight off through the 56 weeks of the study. Contrave is really a combination with the drugs naltrexone and bupropion, which generally seems to reflect a new trend of weight-loss drugs which can be made up of several active ingredient, which may make them more efficient and safer.

    Combo-pilling could be the newest fad or in addition to this the newest to come under scrutiny and so it is just more publicly known lately, comb-pilling for weight loss has been around since the eighties. The biggest reason that employing a combination of pills is starting to become popular is the fact that as of right now there are no long term prescription weight loss supplements that have been approved by the FDA aside from orlistat. The truly disturbing part is that doctors are prescribing these combinations of medications although some people might of the combinations have been rejected or have yet to be licensed by the FDA.

    Seizures are a side effect with Contrave and must not be taken in people who have seizure disorders. The drug could also raise hypertension and heartbeat, and really should not be used in individuals with a history of cardiac arrest or stroke in the previous six months. Blood pressure and pulse should also be measured before beginning the drug and throughout therapy while using drug.

    The FDA also warned that Contrave can raise blood pressure and heartbeat and must 't be used in patients with uncontrolled high blood pressure, as well as by you aren't heart-related and cerebrovascular (circulation dysfunction impacting your brain) disease. Patients having a history of cardiac event or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded in the clinical trials. Those taking Contrave must have their heart-rate and pulse monitored regularly. In addition, since the compound includes bupropion, Contrave comes using a boxed warning to alert health care professionals and patients to the increased chance of suicidal thoughts and behaviors related to antidepressant drugs. The warning also notes that serious neuropsychiatric events are actually reported in patients taking bupropion for stopping smoking.

    Suboxone contains two drugs; buprenorphine and naloxone. The naloxone is irrelevant in the event the addict uses the medication properly, but if your tablet is dissolved in water and injected the naloxone will result in instant withdrawal. When suboxone is employed correctly, the naloxone is destroyed in the liver soon after uptake from the intestines and it has no therapeutic effect. Buprenorphine may be the active substance; it is absorbed under the tongue (and during the entire mouth) but destroyed by the liver if swallowed. There is a formulation of buprenorphine without naloxone called subutex; I manipulate this formulation if the patient has apparent problems from naloxone, including headaches after dosing with suboxone. I also have treated addicts who have had gastric bypass, the location where the first the main intestine is bypassed and also the stomach contents empty in a more distal area of the small intestine. In such cases the naloxone escapes ?first pass metabolism', the procedure with normal anatomy where the drug is taken up through the duodenum and transferred straight away to the liver through the portal vein, where it is quickly and completely destroyed. After gastric bypass naloxone can be taken on by areas of the intestine which are not served through the portal system, causing blood degrees of naloxone sufficient to cause brief, relatively mild withdrawal symptoms.